Introduction
As a multifunctional coenzyme, P5P Powder 41468-25-1 is also called pyridoxal phosphate and PLP (the main metabolically active form of vitamin B6). It participates in several reactions catalyzed by: transamination, 伪-decarboxylation, 尾-decarboxylation, 尾-elimination, 纬 -Elimination, racemization and aldol reaction.
Main Function
P5P powder is the main active form of vitamin B6. It’s main functions are as follows:
1. Participate in the metabolism of “vitamin B12 and folic acid”, participate in the decomposition of “homocysteine”:
If vitamin B6 is deficient, it can not only cause megaloblastic anemia, but also cause hyperhomocysteinemia, which is one of the risk factors of cardiovascular and cerebrovascular diseases, thrombosis and hypertension.According to the clinical findings, it is suggested that on the basis of a balanced diet, appropriate supplement of folic acid, vitamin B6 and vitamin B12 can effectively reduce the plasma homocysteine content, better control blood pressure and better protect blood vessels.
2. Participate in protein synthesis and catabolism, and participate in the metabolism of all amino acids:
鈶?It is involved in the synthesis of heme. If it is deficient, it can cause hypochromic small cell anemia and the increase of serum iron. Therefore, it is often used as an adjuvant therapy to prevent anemia;
鈶?In the synthesis of nicotinic acid from tryptophan, there will be “leprosy” if lacking;
鈶?It participates in the metabolism of amino acids and fat, stimulates the production of white blood cells, and can be used to treat leukopenia;
鈶?Help to repair “oral ulcer” and so on.
3. Participate in the metabolism of glycogen, lipid, sphingomyelin and steroid:
鈶?It can promote the conversion of linoleic acid into arachidonic acid, promote the combination of arachidonic acid and cholesterol, facilitate the transport, metabolism and excretion of cholesterol. In addition, it can inhibit the function of platelets and the formation of fibrin, so it helps to reduce cholesterol and prevent thrombosis;
鈶?It is involved in the metabolism of sphingomyelin and is often used as an adjuvant drug for peripheral neuropathy (such as carpal tunnel syndrome);
鈶?It can stop the effect of steroid hormones. If lacking, it will increase the sensitivity of human body to estrogen, androgen and vitamin D, which will affect the development and prognosis of hormone dependent cancer such as breast cancer, prostate cancer and endometrial cancer.
4. Participate in the synthesis of important neurotransmitters (5-HT, taurine, dopamine, norepinephrine and GABA):
This is widely used in clinical practice, often in the treatment of “infantile convulsion, infantile asthma, vomiting during pregnancy, anxiety, depression, Parkinson’s disease, mental retardation” and other diseases may be used. In addition, by affecting dopamine metabolism in the brain and reducing prolactin secretion, maternal milk secretion can be inhibited.
5. Others:
Such as participating in nucleic acid and DNA synthesis, maintaining appropriate immune function, treating photosensitive dermatitis, rescuing baldness, rescuing isoniazid poisoning and so on.
Application
P5P Powder 41468-25-1 is commonly used in the pharmaceutical and healthcare products.

Specification
ItemsSpecification
Assay98.5~101.0%
IdentificationThe retention time of the major peak of product corresponds to that of the standard
AppearanceOff white to slightly yellow crystalline powder
SolubilityVery slightly soluble in water, soluble in alkali-OH Solution
Melting Point140~145鈩?/p>
pH2.6~3.0
Water鈮?0.0%
Bulk Density/
Pyridoxine HCL鈮?.05%
Heavy Metals鈮?0.0ppm
Microbiological
Total Plate Count
Yeast & Mold
E.Coil
Salmonella
Staphylococcus aureus
Pseudomonas aeruginosa
鈮?,000cfu/g
鈮?00cfu/g
Negative
Negative
Negative
Negative
Flow ChartBulk Health Products
website:http://www.konochem.com/health-products/